🧬 Math derivation for steady-state RNA velocity model
The steady‑state model was the first to enable a mathematical estimation of RNA velocity, and most subsequent methods are modified versions of it or its generalization (the dynamic model in `scVelo`; see our other blogs). It has its limitations and a solid understanding of its underlying mathematics is needed to apply the model effectively. Here, we derive the steady-state model in `scVelo` and `velocyto`.
May 28, 2025
