Improve UMI Normalization that Determines the Downstream Interpretation of Single-Cell Transcriptomes
To be composed soon after paper is published.
Below is only a piece of the project for now.
Contents 1. 🧬 Dissect sctransform()📝Blog | 🐙Git Image credit: Chris Lawton on Unsplash The vst() function applies variance stabilizing transformation to UMI count data using a regularized Negative Binomial regression model. This removes unwanted effects from UMI data and returns Pearson residuals.
Oct 26, 2023
