ScRNAseq

Hyperactivated YAP1 is essential for sustainable progression of renal clear cell carcinoma

Apr 7, 2025

🧬 Bayesian abundance statistics in PRCC
🧬 Bayesian abundance statistics in PRCC

One sample abundance statistics, bayesian vs frequentist

Apr 6, 2025

🧬 Train a high-performance Yolov8 (CNN) model for histological analysis: data augmentation and combating overfitting by Active Learning
🧬 Train a high-performance Yolov8 (CNN) model for histological analysis: data augmentation and combating overfitting by Active Learning

Yolov8, a deep learning tool to

Apr 5, 2025

🧬 CCA reasoning and integration discussion
🧬 CCA reasoning and integration discussion

what is CCA really doing? here we dicepher it and present the mathmatical intuition to appreicate its applicability. Also, discuss the integration.

Apr 3, 2025

🧬 Clinical relevance evaluation in PRCC
🧬 Clinical relevance evaluation in PRCC

I did not find any guidline to evaluate the Clinical relevance of mouse data. Here, I present my method used in the nature communications paper

Mar 31, 2025

🧬 Expressive cord diagram in PRCC
🧬 Expressive cord diagram in PRCC

What could be expressive and concise presentation of cell-cell interaction? Here I write an small tool to draw Expressive cord diagram

Mar 30, 2025

🧬 Determine whether it’s noise or true stem like cells in PRCC
🧬 Determine whether it’s noise or true stem like cells in PRCC

Sparse low number of cells belonging to cancer cell clusters exist in non-treated sample. Are they noise or artifact due to inperfection of integration algorithm or are they true stem like cells prediposted to be prone to tumorogenesis?

Mar 29, 2025

🧬 counteract treatment-specific background in differential expressed gene analysis (huangcong paper)
🧬 counteract treatment-specific background in differential expressed gene analysis (huangcong paper)

The RNAseq dataset involves siRNA treatment, lentivirus infection and shRNA treatment. Here I present a way to formulate the generalized linear models to counteract treatment-specific background during differential expressed gene analysis

Mar 27, 2025

HPV-YAP1 oncogenic alliance drives malignant transformation of fallopian tube epithelial cells

Apr 7, 2024

Single-cell transcriptomics reveals novel strategies for PRCC prevention and treatment

Apr 7, 2023