Targeting the disrupted Hippo signaling to prevent neoplastic renal epithelial cell immune evasion
Apr 7, 2025
Hyperactivated YAP1 is essential for sustainable progression of renal clear cell carcinoma
Apr 7, 2025
🧬 Bayesian abundance statistics in PRCC
One sample abundance statistics, bayesian vs frequentist
Apr 6, 2025
🧬 Train a high-performance Yolov8 (CNN) model for histological analysis: data augmentation and combating overfitting by Active Learning
Yolov8, a deep learning tool to
Apr 5, 2025
🧬 CCA reasoning and integration discussion
what is CCA really doing? here we dicepher it and present the mathmatical intuition to appreicate its applicability. Also, discuss the integration.
Apr 3, 2025
🧬 Clinical relevance evaluation in PRCC
I did not find any guidline to evaluate the Clinical relevance of mouse data. Here, I present my method used in the nature communications paper
Mar 31, 2025
🧬 Expressive cord diagram in PRCC
What could be expressive and concise presentation of cell-cell interaction? Here I write an small tool to draw Expressive cord diagram
Mar 30, 2025
🧬 Determine whether it’s noise or true stem like cells in PRCC
Sparse low number of cells belonging to cancer cell clusters exist in non-treated sample. Are they noise or artifact due to inperfection of integration algorithm or are they true stem like cells prediposted to be prone to tumorogenesis?
Mar 29, 2025
🧬 counteract treatment-specific background in differential expressed gene analysis (huangcong paper)
The RNAseq dataset involves siRNA treatment, lentivirus infection and shRNA treatment. Here I present a way to formulate the generalized linear models to counteract treatment-specific background during differential expressed gene analysis
Mar 27, 2025
HPV-YAP1 oncogenic alliance drives malignant transformation of fallopian tube epithelial cells
Apr 7, 2024