🧬 Determine whether it’s noise or true stem like cells in PRCC
Sparse low number of cells belonging to cancer cell clusters exist in non-treated sample. Are they noise or artifact due to inperfection of integration algorithm or are they true stem like cells prediposted to be prone to tumorogenesis?
Mar 29, 2025
🧬 counteract treatment-specific background in differential expressed gene analysis (huangcong paper)
The RNAseq dataset involves siRNA treatment, lentivirus infection and shRNA treatment. Here I present a way to formulate the generalized linear models to counteract treatment-specific background during differential expressed gene analysis
Mar 27, 2025